SIAT Research
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Mar 29, 2023Researchers Systematic Reviews A New Randomized Clinical Trial"These findings suggest that we must develop new or more aggressive methods to further improve the use of systematic reviews in RCT reports," said Dr. JIA. Systematic reviews can help to justify a new randomized clinical trial (RCT), inform its design, and interpret its results in the context of prior evidence. Therefore, many stakeholders, including ... -
Mar 27, 2023Cellular Growth Rate Reshapes Cell-Fate-Decision Landscape"It is hard to disentangle the global factors, such as growth rate, from the cell-fate-decision processes," said Prof. FU, noting that the growth rates can be varied as the results of the fate deci... Genes and the regulation relationships among them create complex networks that determine cell differentiation trajectories. However, we still cannot understand and predict the cell-fate-decision pr... -
Mar 15, 2023Scientists Elucidate Fine Neural Orchestration of Feeding Processes for the First Time"This study deepens our understanding of the feeding process and the neural regulation mechanism, and provides a new theoretical basis for the treatment of feeding-related disorders," said Dr. WANG. A research team led by Dr. WANG Liping from the Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences has conducted a detailed study of spontaneous behavior during the food ... -
Mar 14, 2023Scientists Develop Magnetic-Acoustic Actuated CAR-T Cell Robots for Precision Antitumor ImmunotherapyIn this strategy, a living CAR T cell microrobot based on magnetic-acoustic sequential actuation for self-controllable targeting and augmented antitumor immunotherapy in solid tumor by artificially... Although chimeric antigen receptor (CAR) T cell therapy has shown incredible success in the treatment of haematological malignancies, its application in solid tumors is unsatisfactory owing to the ... -
Mar 09, 2023Researchers Revealed Molecular Mechanism of Pannexin 2 as an ATP Membrane Pore Channel"Our work illuminated the 3D structures of Panx2 transmembrane protein at the atomic level,"said Prof. YUAN, "it helps to understand the fundamentally biological function of Panx2 which provides an... Recently, a research team collaborated by Prof. YUAN Shuguang from Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences and Prof. ZHANG Huawei from the South University of Science... -
Feb 23, 2023Twin-bioengine Self-adaptive Micro/nanorobots Developed for Gastrointestinal Inflammation Therapy"The transport route is similar to that of the Express Mail Service, which precisely delivers parcels to a distant destination using different transportation facilities," said Prof. CAI. These self... Micro/nanorobots with self-propelling and -navigating capabilities have attracted extensive attention in drug delivery and therapy owing to their controllable locomotion in hard-to-reach body tissu... -
Feb 07, 2023Deep Multi-Magnification Similarity Learning for Histopathological DiagnosisThe team proposed a novel deep multi-magnification similarity learning (DSML) approach that can be useful for the interpretation of multi-magnification learning framework and easy to visualize feat... Precise classification of histopathological images is the ultimate objective of the image analysis.In actual clinical applications, pathologists usually combine information at different magnificati... -
Feb 06, 2023Subtype-specificity in Sleep Regulation in DrosophilaThe team published this study entitled "Subtype-specific roles of ellipsoid body ring neurons in sleep regulation in Drosophila" in the Journal of Neuroscience as the cover/featured article The coherence of regulation of sleep by different brain regions and nuclei in mammals is complex. The ellipsoid body (EB), as a major structure of the central complex of the Drosophila melanogaster...