SIAT Research
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Oct 20, 2023Exploiting Energy Harvesting Technologies to Capture Energy from Human MotionIn this study, researchers developed a lightweight piezoelectric bending beam-based human knee energy harvester to generate electricity during walking. Researchers led by Prof. GAO Fei and Prof. WU Xinyu from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences have exploited energy harvesting technologies to dev... -
Oct 20, 2023Optimizing Cytochrome P450 Network for High Level Production of Quillaic Acid: the Aglycone of Natural Adjuvants"Our work demonstrate the feasibility of using a combinatorial optimization strategy to assemble an enzyme network that catalyzes the multi-step oxidation of inert substrates to synthesize function... The versatile role cytochrome P450s (CYPs) play in nature makes them an important tool in synthetic biology for building microbial cell factories (MCFs) to produce commercially valuable pharmaceuti... -
Oct 16, 2023Circuit-Specific Gene Therapy Brings New Hope for Treatment of Parkinson's DiseaseGiven its success in primate PD model, this brand-new circuit-manipulating gene therapy approach shows great feasibility for treating PD in humans. Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and their collaborators have developed a gene therapy strategy to selectively manipula... -
Oct 16, 2023Researchers Develop a High resolution and High sensitivity MR compatible Brain PET scannerThe purpose of this study is to develop an MR-compatible brain PET scanner that can simultaneously achieve a uniform high spatial resolution and high sensitivity by using dual-ended readout depth e... Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) represents a potent instrument for brain imaging. However, the current spatial resolution of PET scanners utilized for brain imagin... -
Oct 12, 2023Transforming Wastewater into Valuable Chemicals with Sunlight: A Green Breakthrough in Sustainable ManufacturingThe results of their research showcase that these sunlight-activated biohybrids exhibited significantly enhanced BDO production, surpassing yields achievable through bacterial cells alone. Furtherm... Researchers led by Prof. GAO Xiang from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Science and Prof. LU Lu from Harbin Institute of Technology have achieved a no... -
Oct 12, 2023Researchers Propose Novel Data Acquisition Method for High Resolution "Spatial-Temporal-Spectral" CBCT Imaging"We believe this developed suRi method would greatly enhance the imaging performance of the DL-FPD based dual-energy CBCT systems in future," said Prof. GE. Over the past two decades, X-ray flat-panel detector (FPD) has been widely used in medical imaging applications. For the three- and four-dimensional cone-beam computed tomography (CBCT) imaging, FP... -
Oct 10, 2023Stretchable Multi-channel Ionotronic Electrodes for In-situ Dual-modal Monitoring of Muscle-vascular ActivityThe study was published in Advanced Functional Materials on Sep. 26. In-situ dual-modal detection of electrophysiology (EP) and blood oxygen (BO) during the muscle-vascular activity is crucial for healthcare and human-machine interaction. Achieving this requires an ... -
Oct 10, 2023Developing Bone-Targeting Exosome-Mimetics Gene Delivery System for Bone Regeneration"Our study offers a strong and simple strategy for the generation of a considerable quantity of EMs within a brief time frame and customization of their functional attributes, thereby providing a p... Mesenchymal stem cell-derived exosomes (MSC-exos) have shown great potential in the areas of bone regeneration and treatment of age-related diseases. However, low production yield and insufficient ...