SIAT Research
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Jul 10, 2023Novel Positron Emission Tomography Tracer to Visualize SynucleinopathiesPromising lead compound for imaging α-synuclein inclusions in synucleinopathies. Brain imaging scans are powerful tools for diagnosing Parkinson's disease (PD) and ruling out other motor disorders. In PD, the presence of α-synuclein (α-Syn) in Lewy bodies (LBs) and Lewy neuri... -
Jul 04, 2023[待上线] Accelerating Design of Engineered Living Materials through Integrated Technological WorkflowBy harnessing the combined power of bioinformatics, structural biology, and synthetic biology, the team demonstrated the rational design of pili-enabled living materials from scratch. Their systema... The field of engineered living materials (ELMs) aims to develop biomaterials with "living" attributes like autonomous growth, self-healing, and environmental responsiveness, similar to natural livi... -
Jun 27, 2023Exploring the Potential of Periplasmic Biohybrids: A Path to Sustainable Applications"We believe that the construction of periplasmic biohybrids can serve as an invaluable semi-artificial photosynthesis-based model for solar-driven bio-catalysis and sustainability," stated Prof. GA... Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and the University of Chicago have discovered semiconductor nanocluster precipitation ... -
Jun 26, 2023Researchers Unveil the Diversity and Impact of Broad Host Range Plasmids in the Human GutResearchers assembled 820 plasmid-like clusters (PLCs) with high-completeness genomes (comPLCs) The human gut hosts a complex ecosystem comprising an intricate plasmidome with abundant undiscovered plasmids, driving horizontal gene transfer events. Broad host range (BHR) plasmids carrying fit... -
Jun 21, 2023"Telekinesis": Scientists Develop New Technology for Targeted Cancer TherapyThe team has made a breakthrough in the high-precision and high-throughput manipulation technology of phased-array holographic acoustic tweezers for biomedical applications, achieving targeted trea... Acoustic tweezers can control target movement through the interaction of momentum between an acoustic wave and an object. Due to their high tissue penetrability and strong acoustic radiation force,... -
Jun 14, 2023Impaired Inheritance of Parental Histones Accelerates Breast Cancer Growth and MetastasisThis study confirms the crucial role of parental histone inheritance carrying H3K27me3 in maintaining the specific regions of differentiated cells. Chromatin states and their associated epigenetic information play a crucial role in maintaining the identity of cells as they divide. Histone post-translational modifications (PTMs) are important d... -
Jun 07, 2023Confinement Effects of Carbon Nanotubes on Polyoxometalate Clusters Enhance Electrochemical Energy StorageThe electron transfer from CNTs to polyoxometalates reduces the surface charge density of nanotubes, which then weakens the van der Waals forces and suppresses aggregation. Accordingly, SWNTs fille... Carbon nanotubes (CNTs) are considered ideal electrochemical energy storage materials due to their high electrical conductivity, large theoretical surface area, and good chemical stability.However,... -
May 19, 2023Complex Biological Behaviors: How Multiple Oscillators Interact In Live CellsThe researchers modified a previously constructed synthetic oscillator in yeast to acquire a dual responsive oscillator. They validated the system can be synchronized by both periodic α-factor and... In 1665, Christian Huygens observed the synchronization of two pendulum clocks and documented his findings. Oscillatory dynamics, observed not only in physical systems but also in fundamental biolo...