SIAT Research
  • Sep 06, 2023
    Parental Histones Inheritance Safeguards Fate of Embryonic Stem Cell
    This study demonstrates a direct link between DNA replication–coupled histone allocation and cell differentiation. Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) reported a parental histones inheritance safeguard mechanism in which parental histone...
  • Aug 04, 2023
    Quantitative Biological Strategy Helps to Upgrade Vaccines against COVID-19
    The study introduces a novel approach to designing COVID-19 booster shots based on the concept of antigen distance. Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and the University of Hong Kong, along with their collaborators, have proposed a promi...
  • Jul 26, 2023
    Novel Strategy to Accelerate Design of High-Performance Lithium Metal Batteries
    This strategy imparts good mechanical stability and excellent ionic conductivity to the Li metal anode interface, promoting uniform Li deposition while suppressing the growth of Li dendrites. Lithium metal batteries (LMBs) have attracted much attention for their exceptional performance in private electronics and electric vehicle applications. However, their widespread commercialization ...
  • Jul 10, 2023
    Novel Positron Emission Tomography Tracer to Visualize Synucleinopathies
    Promising lead compound for imaging α-synuclein inclusions in synucleinopathies. Brain imaging scans are powerful tools for diagnosing Parkinson's disease (PD) and ruling out other motor disorders. In PD, the presence of α-synuclein (α-Syn) in Lewy bodies (LBs) and Lewy neuri...
  • Jul 04, 2023
    [待上线] Accelerating Design of Engineered Living Materials through Integrated Technological Workflow
    By harnessing the combined power of bioinformatics, structural biology, and synthetic biology, the team demonstrated the rational design of pili-enabled living materials from scratch. Their systema... The field of engineered living materials (ELMs) aims to develop biomaterials with "living" attributes like autonomous growth, self-healing, and environmental responsiveness, similar to natural livi...
  • Jun 27, 2023
    Exploring the Potential of Periplasmic Biohybrids: A Path to Sustainable Applications
    "We believe that the construction of periplasmic biohybrids can serve as an invaluable semi-artificial photosynthesis-based model for solar-driven bio-catalysis and sustainability," stated Prof. GA... Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and the University of Chicago have discovered semiconductor nanocluster precipitation ...
  • Jun 26, 2023
    Researchers Unveil the Diversity and Impact of Broad Host Range Plasmids in the Human Gut
    Researchers assembled 820 plasmid-like clusters (PLCs) with high-completeness genomes (comPLCs) The human gut hosts a complex ecosystem comprising an intricate plasmidome with abundant undiscovered plasmids, driving horizontal gene transfer events. Broad host range (BHR) plasmids carrying fit...
  • Jun 21, 2023
    "Telekinesis": Scientists Develop New Technology for Targeted Cancer Therapy
    The team has made a breakthrough in the high-precision and high-throughput manipulation technology of phased-array holographic acoustic tweezers for biomedical applications, achieving targeted trea... Acoustic tweezers can control target movement through the interaction of momentum between an acoustic wave and an object. Due to their high tissue penetrability and strong acoustic radiation force,...