The Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Science (CAS) was jointly established by CAS, the Shenzhen Municipal Government and The Chinese University of Hong Kong in February 2006.

Guided by its mission—dreams shape the future, applications create the value—SIAT integrates fundamental research, applied development, and industrial transformation. It serves as a strategic hub for addressing China's critical challenges while advancing global scientific progress through interdisciplinary collaboration and open innovation.

SIAT focuses on the multidisciplinary integration and development of Information Technology and Biotechnology (IBT). It comprises nine main affiliated institutes (with a total of 51 research centers): Shenzhen Institute of Advanced Integration Technology (SIAIT); Institute of Biomedical and Health Engineering (IBHE); Institute of Advanced Computing and Digital Engineering (IACDE); Institute of Biomedicine and Biotechnology (IBB); Brain Cognition and Brain Disease Institute (BCBDI); Institute of Synthetic Biology (iSynBio); Institute of Advanced Materials Science and Engineering (AMSE); Institute of Technology for Carbon Neutrality (ITCN); and Institute of Scientific Instrumentation (currently under development).

It is also home to two State Key Laboratories, two National Innovation Centers, one synthetic biology research infrastructure and one brain science research infrastructure, nine National Innovation Laboratories, 34 provincial-level key laboratories and platforms, and 79 municipal-level laboratories and platforms.