SIAT Research
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Mar 01, 2021Researchers Defined A Standard Calculation Methodology for Human Doubly Labeled Water StudiesIn a study published in the Journal Cell Reports Medicine on March 15, professor John Speakman has compiled a database of over 5500 measurements using the technique that has been sponsored by the ... Measuring the energy expenditure of individuals is routinely performed by measuring gas exchange. However, to do that subjects need to either wear a hood or live in a confined chamber. Both of thes... -
Feb 25, 2021Researcher Develop Ex Vivo Reconstructed Multi-sectional Respiratory Organoid in Responds to COVID-19Prof. Li’s team developed ex vivo reconstructed multi-sectional respiratory organoids.SARS-CoV-2 infection was successfully conducted in these respiratory organoids and studied for its infection a... Ever since the beginning of the COVID-19 pandemic, Prof. LI Liang and his team from the Institute of Biomedicine and Biotechnology, the Third People’s Hospital of Shenzhen, and Shenzhen Center for... -
Feb 03, 2021Researchers Develop New Method for Biomanufacturing Vascularized TissueDr. ZHAO Qilong’s group from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences collaboration with Prof. WANG Min’s group at the University of Hong Kong repor... In native tissues and organs, vascularized structures infiltrated within the natural nanofibrous extracellular matrix (ECM) play vital roles in maintaining the functions and metabolisms of tissues ... -
Jan 18, 2021Living Macrophage Drug Promotes Antitumor ImmunotherapyA research team led by Prof. CAI Lintao at the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences developed a "cytopharmaceutical" based on living macrophages. Immunotherapy is one of the most promising approaches to inhibit tumor growth and metastasis by activating host immune functions. However, so far, immunotherapy still exhibits limitations of effica... -
Jan 15, 2021Researchers Reveal Novel Function of Ciliopathy Protein CEP290 in the Initiation of CiliogenesisDr. WEI Qing’s group from Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences reported that ciliopathy protein CEP290 was essential for the initiation of ciliary TZ... Cilia are ubiquitous in human tissues, and the dysfunction of cilia can cause many organ defects and lead to over 35 kinds of human genetic diseases, collectively termed as ciliopathy.The transitio... -
Jan 07, 2021Researchers Develop New Method to Revamp and Minimize Yeast Genomeshowed that a synthetic chromosome arm (synXIIL) could be efficiently reduced, their study was published in Genome Biology on Jan 4. Researchers from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences developed a method termed SCRaMbLE-based genome compaction (SGC) to revamp and minimize the... -
Jan 06, 2021Deep Learning Helps Predicting Occult Peritoneal Metastasis in Stomach CancerA new study published in the JAMA Network Open on Jan. 5 shows that deep learning can help predicting the occult peritoneal metastasis in stomach cancer. It provides a novel and noninvasive approac... Stomach cancer, or gastric cancer, is a common gastrointestinal malignancy. Peritoneal metastasis occurs in a majority of patients with advanced stomach cancer and is considered as an aggressive di... -
Dec 18, 2020Researchers Reveal Seasonal Plasticity in the Mammalian BrainResearchers from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS), in collaboration with colleagues from Germany and Israel have now studied the season... The brain is remarkable for its plasticity, the ability to change and adapt to environmental, behavioral, and metabolic conditions. However, the most studied forms of plasticity occur at very short...