WANG Huaiyu

Date:29-07-2017   |   【Print】 【close


07/2009  Doctor's degree in Organic Chemistry (admitted to the direct PhD program without MS degree and entrance examinations due to the outstanding undergraduate records) 

Technical Institute of Physics and Chemistry, Chinese Academy of Sciences 

Thesis: “Study of PBS and PTFE as biomaterials by the surface modifications using PIII”  

Advisor: Prof. Junhui Ji, Co-advisor: Prof. Paul. K. Chu (City University of Hong Kong) 

07/2004  Bachelor's degree in Pharmaceutical Sciences 

School of Pharmaceutical Sciences, Health Science Center, Peking University 


Research experience                                                                 

01/2017-now          Professor 

Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences 

08/2013-12/2016       Associate Professor 

Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences 

09/2012-08/2013     Postdoctoral Fellow 

The SMAT Laboratory, City University of Hong Kong 


07/2009-08/2012  Senior Research Associate 

03/2007-03/2009  Research Assistant 

The Plasma Laboratory, City University of Hong Kong 


Research Areas                                                                    

u  Bone-related biomaterials 

u  Nano Biomaterials 

u  Surface functionalizations 



01/2017  Member of youth innovation promotion association, Chinese Academy of Sciences 

06/2016  Talented young scientist, Guangdong Province 

11/2013  Overseas High-Caliber Personnel (Level B), ShenZhen 



u  Council Member of National Materials New Technology Development Research Institute 

u  Member of Chinese Society for Biomaterials 

u  Reviewer of journals including Nature Communications, Biomaterials, Scientific Reports, Colloids and Surfaces B: Biointerfaces, Interface Focus, Surface & Coatings Technology, Advanced Biomaterials. 


Publication in Journal                                                              

1.     Ang Gao, Ruiqiang Hang, Wan Li, Wei Zhang, Penghui Li, Guomin Wang, Long Bai, Xuefeng Yu, *Huaiyu Wang(Corresponding author), *Liping Tong, *Paul K. Chu, Linker-free Covalent Immobilization of Heparin, SDF-1α, and CD47 on PTFE Surface by Plasma Treatment for Antithrombogenicity, Endothelialization and Anti-Inflammation. Biomaterials, in press.  IF: 8.402 

2.     Zhibin Li, Jundong Shao, Qian Luo, *Xuefeng Yu, Hanhan Xie, Haidi Fu, Siying Tang, *Huaiyu Wang(Corresponding author), Guangli Han, *Paul K. Chu. Cell-Borne 2D Nanomaterials for Efficient Cancer Targeting and Photothermal Therapy. Biomaterials, 133, pp 37-48, 2017.  IF: 8.402 

3.     Zhengbo Sun, Yuetao Zhao, Zhibin Li, Haodong Cui, Yayan Zhou, Weihao Li, Wei Tao, *Han Zhang, *Huaiyu Wang(Corresponding author), Paul K. Chu, *Xuefeng Yu. TiL4-Coordinated Black Phosphorus Quantum Dots as an Efficient Contrast Agent for In Vivo Photoacoustic Imaging of Cancer. Small, 13, 1602896.  IF: 8.643 

4.     Yuetao Zhao, *Huaiyu Wang(Corresponding author), Hao Huang, Quanlan Xiao, Yanhua Xu, Zhinan Guo, Hanhan Xie, Jundong Shao, Zhengbo Sun, Weijia Han, *XuefengYu, Penghui Li, *Paul K. Chu. Surface Coordination of Black Phosphorus for Robust Air and Water Stability. Angewandte Chemie International Edition, 55, pp 5003-5007, 2016.  IF: 11.994 

5.     Yuetao Zhao, Liping Tong, Yong Li, Haobo Pan, Wei Zhang, Min Guan, Weihao Li, Yixin Chen, Qing Li, Zhongjun Li, *Huaiyu Wang(Corresponding author), *Xuefeng Yu, *Paul K. Chu. Lactose-Functionalized Gold Nanorods for Sensitive and Rapid Serological Diagnosis of Cancer. ACS Applied Materials & Interfaces, 8, pp 5813-5820, 2016.  IF: 7.504 

6.     #Zhibin Li, #Siying Tang, #Beike Wang, Yong Li, Hao Huang, *Huaiyu Wang(Corresponding author), Penghui Li, *Chengzhang Li, *Paul K. Chu, Xuefeng Yu. Metabolizable Small Gold Nanorods: Size-dependent Cytotoxicity, Cell Uptake and In Vivo Biodistribution. ACS Biomaterials Science & Engineering, 2, pp 789-797, 2016.  IF: 3.234 

7.       #Liping Tong, #Wenhua Zhou, Yuetao Zhao, Xuefeng Yu, *Huaiyu Wang(Corresponding author), *Paul K. Chu. Enhanced Cytocompatibility and Reduced Genotoxicity of Polydimethylsiloxane Modified by Plasma Immersion Ion Implantation. Colloids and Surfaces B: Biointerfaces, 148, pp 139-146, 2016.  IF: 3.887 

8.       Changshun Ruan, Yang Hu, Lixin Jiang, Qingqing Cai, Haobo Pan, *Huaiyu Wang (Corresponding author). Tunable Degradation of Piperazine-Based Polyurethane Ureas. Journal of Applied Polymer Science, 131, 40527, 2014.  IF: 1.86 

9.       #Shenglin Mei, #Huaiyu Wang (Co-first author), Wei Wang, Liping Tong, Haobo Pan, Changshun Ruan, Qianli Ma, Mengyuan Liu, Huiling Yang, Liang Zhang, Yicheng Cheng, *Yumei Zhang, *Lingzhou Zhao, *Paul K. Chu. Antibacterial Effects and Biocompatibility of Titanium Surfaces with Graded Silver Incorporation in Titania Nanotubes. Biomaterials, 35, pp 4255-4265, 2014.  IF: 8.402 

10.   Huaiyu Wang, Dixon T. K. Kwok, Ming Xu, Haigang Shi, Zhengwei Wu, Wei Zhang, *Paul K. Chu. Tailoring of Mesenchymal Stem Cells Behavior on Plasma-Modified Polytetrafluoroethylene. Advanced Materials, 24, pp 3315-3324, 2012.  IF: 19.791 

11.   Huaiyu Wang, *Ming Xu, Zhengwei Wu, Wei Zhang, Junhui Ji, *Paul K. Chu. Biodegradable Poly(butylene succinate) Modified by Gas Plasmas and Their In Vitro Functions as Bone Implants. ACS Applied Materials & Interfaces, 4, pp 4380-4386, 2012.  IF: 7.504 

12.   Huaiyu Wang, Ming Xu, Wei Zhang, Dixon T. K. Kwok, Jiang Jiang, Zhengwei Wu, *Paul K. Chu. Mechanical and Biological Characteristics of Diamond-Like Carbon Coated Poly aryl-ether-ether-ketone. Biomaterials, 31, pp 8181-8187, 2010.  IF: 8.402 

13.   Huaiyu Wang, Dixon T. K. Kwok, Wei Wang, Zhengwei Wu, Liping Tong, Yumei Zhang, *Paul K. Chu. Osteoblast Behavior on Polytetrafluoroethylene Modified by Long Pulse, High Frequency Oxygen Plasma Immersion Ion Implantation. Biomaterials, 31, pp 413-419, 2010.  IF: 8.402 

14.   Huaiyu Wang, Junhui Ji, Wei Zhang, Wei Wang, Yihe Zhang, Zhengwei Wu, Yumei Zhang, *Paul K. Chu. Rat Calvaria Osteoblast Behavior and Antibacterial Properties of O2 and N2 Plasma-Implanted Biodegradable Poly(butylene succinate). Acta Biomaterialia, 6, pp 154-159, 2010.  IF: 6.319 

15.   Huaiyu Wang, Junhui Ji, Wei Zhang, Yihe Zhang, Jiang Jiang, Zhengwei Wu, Shihao Pu, *Paul K. Chu. Biocompatibility and Bioactivity of Plasma-Treated Biodegradable Poly(butylene succinate). Acta Biomaterialia, 5, pp 279-287, 2009.  IF: 6.319 

16.   Haidi Fu, Zhibin Li, Hanhan Xie, Zhengbo Sun, Beike Wang, Hao Huang, *Guangli Han, Huaiyu Wang, Paul K. Chu, Xuefeng Yu. Different-Sized Black Phosphorus Nanosheets with Good Cytocompatibility and High Photothermal Performance. RSC advances, 7, pp 14618-14624.  IF: 3.108 

17.   Qi Hao, Hao Huang, Xingce Fan, Xiangyu Hou, Yin Yin, Wan Li, Lifang Si, Haiyan Nan, Huaiyu Wang, Yongfeng Mei, *Teng Qiu, *Paul K. Chu. Facile Design of Ultra-Thin Anodic Aluminum Oxide Membranes for the Fabrication of Plasmonic Nanoarray. Nanotechnology, 28, 105301, 2017.  IF: 3.44 

18.   *Zhe Wang, Shuaifeng Hu, Yupeng Gao, Chen Ye, Huaiyu Wang. Effect of Collagen-Lysozyme Coating on Fresh-salmon Fillets Preservation. LWT-Food Science and Technology, 75, pp 59-64, 2017.  IF: 2.329 

19.   *Wei Zhang, Jun Liu, Haigang Shi, Kun Yang, Pingli Wang, Gexia Wang, Na Liu, Huaiyu Wang, *Junhui Ji, Paul K. Chu. Communication between Nitric Oxide Synthase and Positively-Charged Surface and Bone Formation Promotion. Colloids and Surfaces B: Biointerfaces, 148, pp 354-362, 2016.  IF: 3.887 

20.  Jundong Shao, Hanhan Xie, Hao Huang, Zhibin Li, Zhengbo Sun, Yanhua Xu, Quanlan Xiao, *Xuefeng Yu, Yuetao Zhao, *Han Zhang, Huaiyu Wang, *Paul K. Chu. Biodegradable Black Phosphorus Nanospheres for In Vivo Photothermal Cancer Therapy. Nature Communications, 7, 12967, 2016.  IF: 12.124 

21.   Hanhan Xie, Zhibin Li, Zhengbo Sun, Jundong Shao, *Xuefeng Yu, Zhinan Guo, Jiahong Wang, Quanlan Xiao, Huaiyu Wang, *Ququan Wang, Han Zhang, *Paul K. Chu. Metabolizable Ultrathin Bi2Se­3 Nanosheets in Imaging-Guided Photothermal Therapy. Small, 12, pp 4136-4145, 2016. IF: 8.643 

22.   #Penghui Li, #Yong Li, Zhangkai Zhou, Siying Tang, *Xuefeng Yu, Shu Xiao, Zhongzhen Wu, Quanlan Xiao, Yuetao Zhao, Huaiyu Wang, *Paul K. Chu. Evaporative Self-Assembly of Gold Nanorods into Macroscopic Three-Dimensional Plasmonic Superlattice Arrays. Advanced Materials, 28, pp 2511-2517, 2016.  IF: 19.791 

23.   Beike Wang, *Xuefeng Yu, Jiahong Wang, Zhibin Li, Penghui Li, Huaiyu Wang, Song Li, Paul K. Chu, *Chengzhang Li. Gold-Nanorods-siRNA Nanocomplex for Improved Photothermal Therapy by Gene Silencing. Biomaterials, 78, pp 27-39, 2016.  IF: 8.402 

24.   Zhibin Li, Hao Huang, Siying Tang, Yong Li, *Xuefeng Yu, Huaiyu Wang, Penghui Li, Zhengbo Sun, Han Zhang, Chenli Liu, *Paul K. Chu. Small Gold Nanorods Laden Macrophages for Enhanced Tumor Coverage in Photothermal Therapy. Biomaterials, 74, pp 144-154, 2016.  IF: 8.402 

25.   Siying Tang, Zhinan Guo, Jundong Shao, *Xuefeng Yu, Hanhan Xie, Yong Li, Penghui Li, Ling Zhang, *Ricky K.Y. Fu, Huaiyu Wang, *Paul K. Chu. Drawing-Fabrication of Multifarious Nanoplasmonic Platform on PLLA Paper for Optimized SERS Performance. Journal of Raman Spectroscopy, 47, pp 687-691, 2016.  IF: 2.969 

26.   #Zhengbo Sun, #Hanhan Xie, Siying Tang, *Xuefeng Yu, Zhinan Guo, Jundong Shao, *Han Zhang, Hao Huang, Huaiyu Wang, *Paul K. Chu. Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents. Angewandte Chemie-International Edition, 54, pp 11688-11692, 2015.  IF: 11.994 

27.   Zhinan Guo, *Han Zhang, Shunbin Lu, Zhiteng Wang, Siying Tang, Jundong Shao, Zhengbo Sun, Hanhan Xie, Huaiyu Wang, *Xuefeng Yu, Paul K. Chu. From Black Phosphorus to Phosphorene: Basic Solvent Exfoliation, Evolution of Raman Scattering, and Applications to Ultra-Fast Photonics. Advanced Functional Materials, 25, pp 6996-7002, 2015.  IF: 12.124 

28.   Manping Lin, Huaiyu Wang, Changshun Ruan, Juan Xing, Jinfeng Wang, Yan Li, Yuanliang Wang, *Yanfeng Luo. Adsorption Force of Fibronectin on Various Surface Chemistries and its Vital Role in Osteoblast Adhesion. Biomacromolecules, 16, pp 973-984, 2015.  IF: 5.246 

29.   #Jundong Shao, #Liping Tong, Siying Tang, Zhinan Guo, *Han Zhang, Penghui Li, Huaiyu Wang, *Chang Du, *Xuefeng Yu. PLLA Nanofibrous Paper-Based Plasmonic Substrate with Tailored Hydrophilicity for Focusing SERS Detection. ACS Applied Materials & Interfaces, 7, pp 5391-5399, 2015.  IF: 7.504 

30.   *Wei Zhang, Jun Liu, Haigang Shi, Na Liu, Kun Yang, Lianxin Shi, Bin Gu, Huaiyu Wang, *Junhui Ji, Paul K. Chu. Effects of Plasma-Generated Nitrogen Functionalities on the Upregulation of Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells. Journal of Materials Chemistry B, 3, pp 1856-1863, 2015.  IF: 4.543 

31.   #*Wei Zhang, #Na Liu, Haigang Shi, Jun Liu, Lianxin Shi, Bo Zhang, Huaiyu Wang, *Junhui Ji, *Paul K. Chu. Upregulation of BMSCs Osteogenisis by Positively Charged Tertiary Amines on Polymeric Implants via Charge/iNOS Signaling Pathway. Scientific Reports, 5, 9369, 2015.  IF: 4.259 

32.   *Wei Zhang, Jun Liu, Huaiyu Wang, Ying Xu, Pingli Wang, *Junhui Ji, Paul K. Chu. Enhanced Cytocompatibility of Silver-Containing Biointerface by Constructing Nitrogen Functionalities. Applied Surface Science, 349, pp 327-332, 2015.  IF: 3.387 

33.   Hao Huang, Jiahong Wang, Weihong Jin, Penghui Li, Ming Chen, Hanhan Xie, *Xuefeng Yu, Huaiyu Wang, Zhigao Dai, Xiangheng Xiao, *Paul K. Chu. Competitive Reaction Pathway for Site-Selective Conjugation of Raman Dyes to Hotspots on Gold Nanorods for Greatly Enhanced SERS Performance. Small, 10, pp 4012–4019, 2014.  IF: 8.643 

34.   Min Wu, Lei Li, *Xuefeng Yu, Daquan Zhang, Tianying Sun, Xue Li, Ling Sun, Su Lui, Xiaoqi Huang, Feng Bi, Huaiyu Wang, *Hongyan Zhu, Qiyong Gong. Multifunctional Layered Gadolinium Hydroxide Nanoplates for Ultrahigh Field MRI, CT and Fluorescence Bioimaging. Journal of Biomedical Nanotechnology, 10, pp 3620-3630, 2014.  IF: 4.521 

35.   Changshun Ruan, Nan Hu, Yang Hu, Lixin Jiang, Qingqing Cai, Huaiyu Wang, *Haobo Pan, William W. Lu, *Yuanliang Wang. Piperazine-Based Polyurethane-Ureas with Controllable Degradation as Potential Bone Scaffolds. Polymer, 55, pp 1020-1027, 2014.  IF: 3.684 

36.   *Zhe Wang, Ning Zhang, Huaiyu Wang, Siyao Sui, Xiuxiu Sun, Zhongsu Ma. The Effects of Ultrasonic/Microwave Assisted Treatment on the Properties of Soy Protein Isolate/Titanium Dioxide Films. LWT-Food Science and Technology, 57, pp 548-555, 2014.  IF: 2.329 

37.   #Jiahong Wang, #Beike Wang, Qian Liu, Qian Li, Hao Huang, Li Song, Tianying Sun, Huaiyu Wang, *Xuefeng Yu; *Chengzhang Li, *Paul K. Chu. Bimodal Optical Diagnostics of Oral Cancer Based on Rose Bengal Conjugated Gold Nanorod Platform. Biomaterials, 34, pp 4274-4283, 2013.  IF: 8.402 

38.   Yue Sun, Huaiyu Wang, Tao Xiong, Paul K. Chu, *Dennis C. W. Leung. Feature Development on Prepatterned Elastomer Surfaces Upon Ion Implantation. Microelectronic Engineering, 110, pp 346-349, 2013.  IF: 1.806 

39.   Wei Zhang, Huaiyu Wang, Ayako Oyane, *Hideo Tsurushima, Paul K. Chu. Osteoblast Differentiation and Disinfection Induced by Nitrogen Plasma-Treated Surfaces. Bio-Medical Materials and Engineering, 21, pp 75-82, 2011.  IF: 0.7 

40.   Liping Tong, Dixon T. K. Kwok, Huaiyu Wang, Lijun Wu, *Paul K. Chu. Surface Structures and Osteoblast Activity on Biomedical Polytetrafluoroethylene Treated by Long-Pulse, High-Frequency Oxygen Plasma Immersion Ion Implantation. Advanced Engineering Materials, 12, pp B163-B169, 2010.  IF: 2.319 

41.   P. Vijai Bharathy; *D. Nataraj; Paul K. Chu; Huaiyu Wang; Q. Yang; M.S.R.N. Kiran; J. Silvestre-Albero; D. Mangalaraj. Effect of Titanium Incorporation on the Structural, Mechanical and Biocompatible Properties of DLC Thin Films Prepared by Reactive-Biased Target Ion Beam Deposition Method. Applied Surface Science, 257, pp 143-150, 2010.  IF: 3.387 

42.   Dixon T. K. Kwok, Huaiyu Wang, Yumei Zhang, Kelvin W. K. Yeung, *Paul K. Chu. Effects of Long Pulse Width and High Pulsing Frequency on Surface Superhydrophobicity of Polytetrafluoroethylene in Quasi-Direct-Current Plasma Immersion Ion Implantation. Journal of Applied Physics, 105, 053302, 2009.  IF: 2.068 

43.   Wei Zhang, Yunjun Luo, Huaiyu Wang, Shihao Pu, *Paul K. Chu. Biocompatibility of Silver and Copper Plasma Doped Polyethylene. Surface & Coatings Technology, 203, pp 2550-2553, 2009.  IF: 2.589 

44.   Wei Zhang, Yunjun Luo, Huaiyu Wang, Jiang Jiang, Shihao Pu, *Paul K. Chu. Ag and Ag/N2 Plasma Modification of Polyethylene for the Enhancement of Antibacterial Properties and Cell Growth/Proliferation. Acta Biomaterialia, 4, pp 2028-2036, 2008.  IF: 6.319 



1.         Huaiyu Wang; Paul K. Chu. Chapter 4 of Characterization of biomaterials: Surface characterization of biomaterials, edited by Amit Bandyopadhyay and Susmita Bose, Elsevier, pp 105-174, 2013.