SHU Wu

Date:29-07-2017   |   【Print】 【close

Experience 

Education 

1)    PhD, Biological Chemistry, PhD awarded: 26/10/2007. 

Max-Planck Institute for Biological Cybernetics, and University of Tuebingen, Germany. 2005 – 2007. 

2)    MSc, Biological Chemistry, Msc awarded: 01/07/2000. 

Lanzhou University, Lanzhou, P.R. China. 1997 - 2000.  

3)    BSc, Biology, BSc awarded: 01/07/1990.   

Department of Biology, Peking University, Beijing, P. R. China. 1986- 1990.  

 

Employment 

1)    Professor, Principal Investigator, 10/2012 – Present,  

Shenzhen Institutes of Advanced Technology, Chinese Academy Sciences.  

2)    EPSRC Independent Postdoctoral Research Fellow, 10/2009 – 09/2012 

Department of Chemistry, University of Leicester, U.K. 

3)    Postdoctoral Research Associate, 02/2008 – 09/2009 

Department of Chemistry, University of Leicester, U.K. 

4)    Lecturer, Research Group Leader of Medicinal Chemistry, 08/2000-12/2004. 

School of Life Sciences, East China University of Sciences & Technology, Shanghai, China.  

  

Research Interests 

Current research in my group involves studies in chemistry, biology, and bio-nanomaterial sciences. A special emphasis is placed on the design and synthesis of peptides, peptoids and bionanomaterials to address problems of significance in biology and medicine such as inhibiting cancer proliferation, regulating gene transcription and drug delivery. 

 

Representative Publications 

1.    Wu CL, Pan ZY, Yao GY, Wang W, Fang LJ*, Su W*. Synthesis and structure-activity relationship studies of Teixobactin analogues. RSC Advances. 2017, 7, 1923-1926. 

2.    Tan Y, Wang W, Wu C, Pan Z, Yao G, Fang L, Su W*. Myristic acid-modified thymopentin for enhanced plasma stability and immune-modulating activity. Int Immunopharmacol. 2017, 47, 88-94. 

3.    Liu XH, Wang YJ, Yang DX, Zhang JL, Liu DS* and Su W*. Catalytic asymmetric inverse-electron-demand 1, 3-depolar cycloaddition of C, N-cyclic azomethine imines with azlactones: an easy access to chiral tricyclic tetrahydroisoquinolines. Angew Chem int ed, 2016, 55, 8100-8103. 

4.    Liang H, Ao LJ, Hu DH, Wang W, Sheng ZH, and Su W*. Magneto-plasmonic nanocapsules for multimodal-imaging and magnetically guided combination cancer therapy. Chemistry of Materials, 2016, 28, 5896-5904. 

5.    Huang L, Ao LJ, Wang W, Hu DH, Sheng ZH, and Su W*. Multifunctional magnetic silica nanotubes for MR imaging and targeted drug delivery. Chem Commun, 2015, 51, 3923—3926. 

6.    Wang LQ, Li D, Yang DX, Wang KZ, Wang J, Wang PX, Su W* and Wang R*. Catalytic Asymmetric Ring-Opening Reactions of Aziridines with 3-Aryl-Oxindoles. Chemistry – An Asian Journal, 2016, 5, 691-695. 

7.    Yao GY, Pan ZY, Wu CL,Wang W, Fang LJ*, and Su W*. Efficient synthesis and stereochemical revision of Coibamide A. J Am Chem Soc, 2015, 137, 13488-13491. 

8.    Fang LJ,Yao GY,Pan ZY,Wu CL,Wang HS,Burley GA,and Su W*. Fully automated synthesis of DNA-Binding Py-Im polyamides using a Triphosgene coupling strategy. Org. Lett. 2015, 17, 158−161 

9.    Ao LJ,Wang B, Liu P, Huang L, Yue CX, Gao DY, Wu CL, Su W.* A folate-integrated magnetic polymer micelle for MRI and dual targeted drug delivery. Nanoscale, 2014, 6, 10710-10116.  

10.  Fang LJ, Wu CL, Yu ZD, Shang P, Cheng YX, Peng YF*, and Su W*. Triphosgene-mediated couplings in the solid phase: Total synthesis of Brachystemin A. Eur. J. Org. Chem. 2014, 7572–7576 

  

Intelligent property Issued Patent 

1.     Su W, Burley G. Process for Preparing Polyamides. (2014), US 8674020 B2. 

Published Patent Applications 

1.     Su W, Fang LJ. A method for the preparation of Cyclosporine.  PCT/CN2014/093969/.  

2.     Su W, Fang LJ, Pan ZY. Synthesis of Coibamide A Analouges. 201510648096.7 

3.     Su W, Li HC, Fang LJ, Liu K, Pan ZY. Synthesis and Applications of PLK1 inhibitors. 201510916228.X 

  

Honor 

“One Hundred Talents Program” from Chinese Academy of Sciences 

wu.su@siat.ac.cn 

http://www.siat.cas.cn/jgsz2016/jgdh2016/kybm2016/yys2016/yjdy20162/nmyljsyjzx2016/zxtd_125401/201605/W020160509523573056200.pdf