Center for Energy Metabolism and Reproduction

Introduction

Center for Reproductive and Healthy Development was established in 2013. At present, the team has a total of1 chief scientist, 5 researchers, 7 post doctors and 16 students. Among them, there are 8 master students and 7 doctoral students. The research mainly involves hotspots such as reproduction, metabolism, host-pathogen interaction mechanism, biological materials, peptides, and targeted drug delivery.

Main Research Areas

Reproductive endocrinology associated diseases: polycystic ovary syndrome, gestational diabetes mellitus, endometriosis, osteoporosis, the relationship of obesity and function of ovary, testis and uterus.   

Reproductive cancer: ovary cancer, choriocarcinoma, and prostatic cancer, specific nanoparticle targeted medicine to reproductive disease.

Intrauterine microenvironment and gestational diseases: development of placenta and associated diseases, preeclampsia, placental specific exocrine,exploration of contraceptive vaccine.  

Biological three dimensional culture and 3D printing: in vitro three-dimensional culture of uterus, ovarian follicles.

The main focus of my work is to understand the causes and consequences of variation in energy balance in animals and humans. Understanding how animals acquire energy and the factors that limit its use provides a useful framework for understanding many phenomena including reproductive performance, obesity, ageing and life history evolution. 

Male reproductive system: The classic model biological nematodes and fruit flies are mainly used as a model, combined with mammalian cell and mouse experiments, to study the mechanism of organelle cilia and sperm flagella and related human disease mechanisms. 

Immune system related diseases: pathogen infection mechanism, host immune response and development mechanism, combined with clinical application to develop new diagnostic and therapeutic methods. 

Peptide and biological material related research: GPCR, functional peptides in metabolic diseases, biological materials, adult stem cells and tissue engineering repair and regeneration. 

Mechanism research on reproductive and metabolic diseases; Biomaterials and targeted drug delivery. 

Researchers

  • John Roger Speakman

    Title:Professor
    Email:j.speakman@siat.ac.cn
    Areas of Interest:Obesity and energy metabolism

  • ZHANG Jian

    Title:Professor
    Email:jian.zhang@siat.ac.cn
    Areas of Interest:Metabolic diseases

  • LEI Xiaohua

    Title:Associate Professor
    Email:xh.lei@siat.ac.cn
    Areas of Interest:Mechanism research on space environment on mammalian embryonic development

  • REN Peigen

    Title:Professor
    Email:pg.ren@siat.ac.cn
    Areas of Interest:Peptide ligands and G protein-coupled receptors

  • LI Liang

    Title:Associate Professor
    Email:liang.li@siat.ac.cn
    Areas of Interest:Host-Pathogen Interaction Mechanism

  • WEI Qing

    Title:Professor
    Email:qing.wei@siat.ac.cn
    Areas of Interest:Classic model organisms nematodes

  • ZHAO Huashan

    Title:Senior Engineer
    Email:hs.zhao@siat.ac.cn
    Areas of Interest:Mechanism research on reproductive and metabolic diseases


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