WANG Pu

Date:29-07-2017   |   【Print】 【close

Dr. Pu Wang, Professor, received his Ph.D. degree in Virology and Immunology from South Dakota State University in 2000 and completed his postdoctoral training at University of Pennsylvania. He has participated in several NIH research projects and published over 20 papers in peer reviewed journals, such as Journal of Clinical Investigation, PNAS, Cancer Research, Diabetes and Journal of Virology. He is investigating the mechanisms utilized by Epstein-Barr virus (EBV) to induce tumors and developing methods for therapeutic intervention for cancer and chronic inflammatory diseases. 

  

  

Pu Wang, PhD 

Shenzhen Institutes of Advanced Technology,  

Chinese Academy Sciences, Shenzhen, Guangdong, China 

Tel: 075586585253 (O) and 13266525178C) 

E-mail: pu.wang@siat.ac.cn 

Professional experience   

2013-prensent, Professor, Shenzhen Institutes of Advanced Technology, Chinese Academy Sciences, Shenzhen, Guangdong, China 

1. Development of therapeutic vaccine for HPV,EBV and HBV 

2. Development of therapeutic monoclonal antibodies for cancer, virus diseases and autoimmune diseases 

3. Studies of hepatoprotective and immunomodulatory herbal Plants. 

2003-2013  Postdoctoral Fellow, Associate Staff Scientist, Staff Scientist,The Wistar Institute, Philadelphia, PA 

2000-2003 Postdoctoral Fellow, School of Medicine, University of Pennsylvania, Philadelphia, PA  

1994-2000 Graduate Research Assistant, South Dakota State University, Brookings, SD PhD degree 

PhD, Virology and Immunology, South Dakota State University, Brookings, SD, USA,  

  

Selected publications 

Wei Zheng, Qilan Wang, Xiaohua Lu, Qiangqiang Shi, Junhui Zou,Yanduo Tao, Pu Wang (2016)  Protective Effects of Dracocephalum Heterophyllum in ConA-Induced Acute Hepatitis, Mediator of Inflammation , 2016 Jul 25, 2684321  

Wang P, Rennekamp AJ, Yuan Y and. Lieberman PM. (2009), Topoisomerase I is required for Zta-dependent transcription activation and replication of Epstein-Barr virus. J Virol. Aug; 83(16):8090-8.  

Wiedmer A, Wang P ,  Zhou J,. Rennekamp AJ, Tiranti V, Zeviani M and Lieberman PM (2008).Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication. J Virol. May; 82(9):4647-55. 

Wang P, Day L, Dheekollu J and Lieberman PM. (2006), Multivalent sequence recognition by Epstein-Barr virus Zta requires cysteine 171 and extension of canonical B-zip domain.  J Virol. Nov; 80 (22):10942-9.  

Anand S, Wang P, Yoshimura K, Choi IH, Hilliard A, Chen YH, Wang CR, Schulick R, Flies AS, Flies DB, Zhu G, Xu Y, Pardoll DM, Chen L, Tamada K.  (2006), Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis. J. Clin. Invest. Apr; 116 (4):1045-51. ( 5-Year Impact Factor :16.641) 

Wang P, Day L, Dheekollu J, Lieberman PM. (2005), A redox-sensitive cysteine in Zta is require d for Epstein-Barr virus lytic cycle DNA replication. J. Virol. Nov; 79 (21):13298-309.  

*Zheng SJ, *Wang P, Tsabary G and Chen YH (2004), Critical roles of TRAIL in hepatic cell death and hepatic inflammation. J. Clin. Invest. 113:58-64 (* Co-first authors)